Pediatric Learning Health Networks in Solid Organ Transplantation—Engaging all Stakeholders to Achieve Health for Children Who Require Transplantation

Pediatric Transplantation. Background: Learning Health Networks (LHN) have evolved within medicine over the past two decades, but their integration into transplantation has been more recent. This paper describes three LHNs in end-stage organ disease/transplantation, their common and unique features, and how their actor-oriented architecture allowed for rapid adaptation to meet the needs of their patients and practitioners during the COVID-19 pandemic. The structure and focus of the Improving Renal Outcomes Collaborative (IROC), Starzl Network for Excellence in Pediatric Transplantation (SNEPT), and the Advanced Cardiac Therapies Improving Outcomes Network (ACTION) are reviewed, discussing the critical role of patient and family engagement, focusing on collaboration with Transplant Families.